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  • 5 in mice, at which time point erythropoiesis and myelopoiesis predominate in the presumptive red pulp, persisting until one week after birth 12, 13, while the structure of the white pulp surrounded by the marginal sinus gradually becomes organized with the proper positioning of T and B cell areas after birth 14 zithromax chlamydia 4 According to the presence or absence of estrogen receptors ER, progestin receptors PR and human epidermal growth factor receptor 2 HER2, these molecular subtypes have been defined as Luminal A ER and PR positive, HER2 negative, low Ki67, Luminal B ER and or PR positive, HER2 positive or high Ki67, HER2 enriched ER and PR negative, HER2 positive and triple negative TNBC ER, PR, HER2 negative